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Hi,

what is the possibility of a restricting only one column from a row to a user.

As a example, 

    I need to hide  'Over Delivery Tolerance' column(purchase order window->Line)  from user A.

    Can user permisson be limited to prevent usage of this column ?

 @Darshana Herath,

Best way of restricting/hiding a column from a user is a base profile. You can create a base profile by hiding the relevant column and assign it to the user/s through Solution Manager> Security > Users> Create User window.