Hi Kyle,
First concern I would have is the amount of memory resources kept for the planning as you are increasing the area covered so more must be analyzed etc.
Howevet, I know some companies managing this more on a national level in Europe but perhaps utilize node level segregation to manage the loas across different servers.
Other than just experimenting and see what happens in your case as companies are different, you might see if you can get a business consultant familiar with DSE planning involved to discuss your requirements and concerns.